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Anwit completed his Bachelors in Microbiology from the University of Pune and Masters in Microbiology from The Maharaja Sayajirao University of Baroda in India. After gaining some research experience in mammalian cell biology at the Indian Institute of Science, Bangalore, he joined the Sawarkar Lab at the Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany funded by the CIBSS Centre For Integrative Biological Signalling Studies in 2019. Anwit is a part of the Spemann Graduate School of Biology and Medicine (SGBM). Anwit moved to the MRC Tox Unit, Cambridge along with the lab in 2021, where he is continuing his PhD.


Research interests:

Each mammalian cell can sense changes in environmental conditions, and respond to it in order to better survival the change. Anwit is interested in delineating the regulatory network at the heart of these stress signalling pathways. Towards this goal, he is harbouring the power of CRISPR genome-scale genetic screening to look for the regulators of heat shock response.



Key publications: 

1. Rawat, P., Boehning, M., Hummel, B., Aprile-Garcia, F., Pandit, A. S., Eisenhardt, N., ... & Sawarkar, R. (2021). Stress-induced nuclear condensation of NELF drives transcriptional downregulation. Molecular cell, 81(5), 1013-1026.
2. Mishra, S., Tamta, A. K., Sarikhani, M., Desingu, P. A., Kizkekra, S. M., Pandit, A. S., ... & Sundaresan, N. R. (2018). Subcutaneous Ehrlich Ascites Carcinoma mice model for studying cancer-induced cardiomyopathy. Scientific reports, 8(1), 5599.
3. Sarikhani, M., Maity, S., Mishra, S., Jain, A., Tamta, A. K., Ravi, V., ... & Sundaresan, N. R. (2018). SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis. Journal of Biological Chemistry, 293(14), 5281-5294.


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MRC Toxicology Unit
Gleeson Building
Tennis Court Road


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