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Welcome to the MRC Toxicology Unit

The Medical Research Council (MRC) Toxicology Unit is a leading International Research Institute within the School of Biological Sciences, University of Cambridge. The Unit delivers mechanistic toxicology research, pursuing hypothesis-driven toxicological questions with a particular focus on the study of the causal links between exposure to endogenous and exogenous toxicants, molecular initiating events and adverse outcome pathways. The Unit's overall aims are to carry out pioneering research which leads to improved health and to train and mentor the next generation of toxicologists.


Professor Anne Willis is Director of the MRC Toxicology Unit.  Anne was appointed as a member of the European Molecular Biology Organisation in 2015, and in 2017 awarded an OBE for services to biomedical sciences and supporting the careers of women scientists.

Professor Anne Willis OBE


Dr Kiran Patil has been appointed as Deputy Editor for the open access journal: 'PLOS Computational Biology'

23 June 2021

This open access journal explores the " application of computational methods among disparate areas of biology" (PLOS Computaional Biology: Journal Information ). Editorial Board: PLOS Computational Biology: A Peer-Reviewed Open-Access Journal

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Nature Communications featured article: Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report

1 March 2021

A recently publised article from Dr. James Thaventhiran's group about the potential treatment effect of remedesvir in COVID-19 patients was chosen as a featured paper by Nature Communiactions. The scientific achivement is highlighted under the topic of "Microbiology and Infectious diseases" in the journal's January issue .

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Cryo-EM structural analysis reveals Caspase-8 catalytic domain architecture for co-ordinated control of cell fate

17 February 2021

Marion MacFarlane, MRC Investigator and Deputy Director at the MRC Toxicology Unit is the senior author of a new study published in Nature Communications which reveals how ‘Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate’. “The core FADD...

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We are currently inviting applications for the following positions:

Position Closing Date
Lab Tech (Tissue Culture) 12 Aug 2021
Finance Co-ordinator 10 Aug 2021
Administrator 6 Aug 2021
Research Associate (Patil lab) 5 Aug 2021
Laboratory Technician (Operations) 3 Aug 2021
IT Specialist (Maternity cover) 27 July 2021

Further details on each vacancy can be found our recruitment page.