Scientists have found that the loss of the PDCD4 protein affects cell adhesion – how cells interact and attach with neighbouring cells and structures – which could make it easier for cancer cells to detach and metastasise. PDCD4 (Programmed Cell Death Protein 4) is a well-documented tumour suppressor – a protein that helps...

The MRC Toxicology Unit has been awarded Silver Laboratory Efficiency Assessment Framework (LEAF) accreditation. This is a significant achievement in the Unit’s journey to conduct research more sustainably. LEAF is a standard for sustainability and efficiency of laboratories that was developed by University College London...

Scientists have found that stopping translation elongation, a key step in protein production, can slow the growth of cancer cells. They identified that this works by reducing the energy producing capability of the mitochondria. We can use this finding to develop a treatment for cancers that are reliant on the mitochondria...

Professor Kiran Patil, MRC Investigator at the MRC Toxicology Unit has been given the Clarivate Web of Science Highly Cited Award for 2025 . The highly cited program celebrates individuals who have demonstrated a significant influence on their field of research and the wider scientific community. The researchers selected...