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Biography:

Liza joined the Toxicology Unit in 2018, following completion of her PhD on ‘Mechanistically relevant biomarkers of pulmonary inflammation arising from exposure to traffic-related air pollution’ at Imperial College, London and Public Health England as part of the ITTP scheme. During this time, she spent a year with Dr. Ian Mudway’s group at King’s College, London (now Imperial College), learning techniques relevant to particulate toxicology.

As a UKRI-funded research fellow and member of the Willis Group, her project uses omics-based strategies to identify adverse outcome pathways that associate with exposure to commonly-encountered air pollutants. Often these studies employ samples produced through human exposures and are performed in collaboration with colleagues at the University of Leicester, RIVM National Institute for Public Health and the Environment and the University of Umeå. Specifically, these projects include dual proteomic and transcriptomic profiling of the host-bacterial response to brake dust exposuremetabolomic urinalysis of responses to aviation-related ultrafine particles and multi-platform characterisation of bronchial responses to wood-smoke exposure.

Outside of the laboratory, Liza is a keen member of several public engagement committees.  In 2018, she participated in the MRC I’m a Scientist web-chat competition where students voted for her to receive £500 funding for public engagement work. This contributed to an interactive exhibition for school children that ran alongside Michael Pinksy’s air pollution pods on Clean Air Day in Manchester. Liza has also participated as a guest for podcasts, radio, BBC news items, television round-tables and Shambala festival.

Key Publications:

1. Travaglio et al. (2021). Links between air pollution and COVID-19 in England. Environ. Pollut. 268.

2. Selley et al. (2019). Brake dust exposure exacerbates inflammation and transiently compromises phagocytosis in macrophage. Metallomics 12, 371–386.

3. Selley et al. (2019).  The potential of omics approaches to elucidate mechanisms of biodiesel-induced pulmonary toxicity. Part. Fibre Toxicol. 16.

4. Ghezzi et al. (2018). Oxidative Stress and Inflammation Induced by Environmental and Psychological Stressors: A Biomarker Perspective. Antioxidants Redox Signal. 28.

 

Rutherford Fellow (UKRI)

Contact Details

MRC Toxicology Unit
Gleeson Building
Tennis Court Road
Cambridge

CB2 1QR

Telephone and Email

+44 (0)1223 3 34537

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