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Mitochondrial damage: the missing piece in understanding the side-effects from antipsychotics?

6 September 2023

Researchers from the MRC Toxicology Unit, in collaboration with the MRC Mitochondrial Biology Unit in Cambridge, have uncovered why individuals who are prescribed some antipsychotic drugs can develop movement disorders. How these side-effects might develop was not clear – until now - and it is all linked to damage to the...

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Microbiome: The Kingdom of the Gut

24 August 2023

The work of the Patil lab is featured in this story by the University of Cambridge. It explores how Cambridge scientists are trying to get a grasp on the basic rules these bacteria play by, in the hope of understanding not only what’s going on in there, but how we might be able to use our microbiome to our advantage.

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Tiago Marques Pedro selected for international toxicology conference

23 August 2023

tiago.jpg Tiago Marques Pedro, a PhD student in the MacFarlane lab, has been selected to present his research at the Gordon Research Conference on Cellular and Molecular Mechanisms of Toxicity. "Alongside the amazing speakers, innovative science and hiking excursions, I was chosen to give a short talk based on my poster...

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The Mirror report discovery that could help tailor vaccinations for people in future

31 July 2023

The Mirror covered the latest exciting research from the Thaventhiran lab in collaboration with researchers across the University of Cambridge. Described as a "huge step forward" by Dr Miriam Stoppard, the discovery made by Unit researchers may explain why, even among vulnerable patient groups, some have better responses...

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Tracing toxic ‘tyre dust’ pollution in the air to assess human exposure

20 July 2023

When you think of traffic pollution, what comes to mind? Exhaust fumes? What about miniscule pieces of tyre rubber floating around in the atmosphere? Tyre wear particles make up a significant portion of air pollution in UK cities and is only projected to increase over the next decade. In fact, it is estimated that about 1...

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Unit hosts annual ITTP Summer School

19 July 2023

Last week, the Unit hosted the annual ITTP Summer School from 10th - 13th July. Each year, four studentships are awarded as part of the MRC Integrative Toxicology Training Partnership (ITTP) to train the next generation of toxicologists. These students study at organisations across the UK from Swansea, to Newcastle, to...

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Unit receives Bronze 'Green Impact' Award for 2022-23

17 July 2023

We are delighted to have received a Bronze accreditation in the national Green Impact scheme in our first year of participating. This award recognises the work of our Green Impact Team, led by Unit members Sina Beier, Laraine Crossland and Alex Fulton, as well as the wider support from our Green Committee. img_1621.jpeg...

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Searching for new anti-cancer compounds in bacteria

30 June 2023

Cancer is something that has impacted all of us either directly or indirectly and is a leading cause of death globally. As a result, there is an urgent and ongoing need to discover and develop new treatments to tackle this disease more efficiently. Interestingly, most of the small-molecule drugs that have been approved as...

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‘Ageing’ immune cell levels could predict how well we respond to vaccines

27 June 2023

Researchers from the MRC Toxicology Unit have identified a signature in the blood that could help predict how well an individual will respond to vaccines. The discovery, published today in the journal Nature Communications, may explain why, even among vulnerable patient groups, some individuals have better responses to...

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Unit host visiting PhD students from Netherlands to identify potential new collaborations

7 June 2023

On Friday 2nd June, a group of 25 PhD students from Wageningen University & Research (WUR), The Netherlands, visited the Unit as part of their tour of UK toxicology research facilities and to identify potential future collaborations. We were treated to a day of exciting flash presentations from PhD students from both...

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