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Researchers test a drug that may allow more cancer patients to benefit from immunotherapy in the future

3 November 2020

Immunotherapy can be a lifesaver for cancer patients, but some patients' tumours don't respond well to this treatment. However, researchers are encouraged by a recent clinical trial that suggests that it may be possible to expand immunotherapy to help more people in the future. Immunotherapy works by marshalling the body's...

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Air pollution from brake dust may have same harmful effects on immune cells as diesel exhaust

20 January 2020

Metal particles from the abrasion of brake pads - up to a fifth of fine particulate matter (PM2.5) air pollution at roadsides - may cause inflammation and reduce the ability of immune cells to kill bacteria, a new study has found, similarly to particles derived from diesel exhaust. The scientists, primarily funded by the...

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New exciting paper from the Willis Lab

18 December 2019

We are pleased to announce a new paper from the Willis lab, which made front cover of science signaling, shows the common chemotherapy doxorubicin can promote the migration of cancer cells through phosphorylation of a translation factor. Please see the links to the article published in Science Signaling below: Summary...

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Catching lung cancer early using only a sample of blood

14 February 2019

In this video, a summary of Miguel’s group latest study, modelling pre-cancerous lung tumours in mice to determine if evidence of these early tumours could be detected in the blood

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'PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair'

25 September 2018

Published in @NatureComms today by scientists at @MRC_TU - 'PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair'

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