Our 'CAR-T cell' temporary tattoo was designed for the Chapman lab to represent their research as part of the Tattoo my Science project.
CAR-T cellCAR-T cell therapy is a new type of cancer treatment that involves engineering a patient's immune cells to help them attack the tumour more effectively. They work really well for some cancers, but they can have complicated toxic side effects too. We are studying why and how these toxic side effects can develop, so that we can make CAR-T cell therapy safer and more widely available. Design by Wiktoria Parol |
Chapman labUnderstanding and mediating the toxicity of CAR-T cell therapy CAR-T cell therapy is a revolutionary new cancer treatment that involves engineering a patient’s immune cells to help them attack the tumour more effectively. They are highly effective for certain types of cancer, but their use is complicated by potentially life-threatening toxicity. It is not clear why side-effects are severe in some patients and mild or non-existent in others, although it likely relates to differences in immune systems between individuals. We are using new technologies to help us better understand the immune system and to investigate how and why toxicity develops. We will use this knowledge to design interventions that make CAR-T therapy safer and more widely available. |
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