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Biography:

Kiran studied Chemical Engineering at the Indian Institute of Technology (Mumbai, India). He moved to the Technical University of Denmark (DTU) to work with Prof. Jens Nielsen and obtained his PhD  in Systems Biology. Kiran was then appointed as Assistant Professor at DTU where he worked on transcriptional regulation and metabolic engineering. In 2010, Kiran joined the Structural and Computational Biology Unit at the European Molecular Biology Laboratory (EMBL-Heidelberg, Germany). He was appointed Director of Research at the MRC Toxicology Unit in 2019.

Key Publications:

(Find full list of publications here: Google Scholar)

1. Klunemann, M., S. Andrejev, S. Blasche, A. Mateus, P. Phapale, S. Devendran, J. Vappiani, B. Simon, T. A. Scott, E. Kafkia, D. Konstantinidis, K. Zirngibl, E. Mastrorilli, M. Banzhaf, M. T. Mackmull, F. Hovelmann, L. Nesme, A. R. Brochado, L. Maier, T. Bock, V. Periwal, M. Kumar, Y. Kim, M. Tramontano, C. Schultz, M. Beck, J. Hennig, M. Zimmermann, D. C. Sevin, F. Cabreiro, M. M. Savitski, P. Bork, A. Typas and K. R. Patil. Bioaccumulation of therapeutic drugs by human gut bacteria. Nature 597(7877): 533-538. (2021)

2. Machado, D., Maistrenko, O.M., Andrejev, Yongkyu Kim, Peer Bork, Kaustubh R. Patil & Kiran R. Patil. Polarization of microbial communities between competitive and cooperative metabolism. Nat Ecol Evol (2021). https://doi.org/10.1038/s41559-020-01353-4

3. Machado D, Andrejev S, Tramontano M, Patil KR. Fast automated reconstruction of genome-scale metabolic models for microbial species and communities. Nucleic Acids Research. doi: 10.1093/nar/gky537 (2018)

4. Maier L, Pruteanu M, Kuhn M, Zeller G, Telzerow A, Anderson EE, Brochado AR, Fernandez KC, Dose H, Mori H, Patil KR, Bork P, Typas A. Extensive impact of non-antibiotic drugs on human gut bacteria. Nature. doi: 10.1038/nature25979 (2018)

5. Tramontano M, Andrejev S, Pruteanu M, Klünemann M, Kuhn M, Galardini M, Jouhten P, Zelezniak A, Zeller G, Bork P, Typas A, Patil KR. Nutritional preferences of human gut bacteria reveal their metabolic idiosyncrasies. Nature Microbiol. doi: 10.1038/s41564-018-0123-9 (2018)

6. Ponomarova O, Gabrielli N, Sévin DC, Mülleder M, Zirngibl K, Bulyha K, Andrejev S, Kafkia E, Typas A, Sauer U, Ralser M, Patil KR. Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow. Cell Systems. DOI: 10.1016/j.cels.2017.09.002 (2017)

7. Zelezniak A, Andrejev S, Ponomarova O, Mende DR, Bork P & Patil KR. Metabolic dependencies drive species co-occurrence in diverse microbial communities. Proc. Natl. Acad. Sci. U.S.A. 112 (20), 6449-6454 (2015).

MRC Investigator

Contact Details

MRC Toxicology Unit
Gleeson Building
Tennis Court Road
Cambridge

CB2 1QR

Telephone and Email

+44 (0)1223 3 35640

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