Biography
James studied biomedical science at the University of Sheffield, graduating with an MBiomedSci degree in 2021. Following this, he joined the Martins programme for a PhD.
Research Interests
Drugs and environmental toxins often have off-target effects on cells throughout the body. One of the organs most at risk from such effects of orally-administered drugs is the gut. Recent research has shown that organs in the body do not exist in isolation but communicate with each other using multiple different mechanisms in response to local stresses.
My research uses the fruit fly, Drosophila melanogaster, to model the impacts of off-target effects of drugs and toxins on different organs both genetically and pharmacologically. I am particularly interested in the links between adverse drug reactions in a single organ, such as the gut, and the effects this has on peripheral organs - in particular changes to whole organism homeostasis and behaviour.
