skip to content



Claudia studied a BSc in Biomedical Sciences at the University of Barcelona (Barcelona, Spain). She then carried out a MSc in Bioinformatics and a PhD in Biomedicine at the Pompeu Fabra University (Barcelona, Spain). During her BSc, Claudia studied the metabolic reprogramming of lymphocytes under proliferation at Dr Ramon Bartrons lab (University of Barcelona). In her MSc and PhD at the laboratory of Dr Nuria Lopez Bigas (IRB Barcelona), Claudia focused on the computational analysis of somatic mutations in cancer. Claudia started her postdoctoral training at Sarah Aitken group in October 2022.


Research interests:

Our cells accumulate damage in their genetic material during life. Understanding the sources and mechanisms behind this damage, as well as its cellular consequences, can help us to improve how we understand human health and disease. This is particularly relevant in the context of the liver, a major organ that is exposed to different sources of damage that plays a key role in human physiology. In her postdoc, Claudia leverages bioinformatic and image analysis techniques to study how normal and cancer cells from the liver accumulate changes in their DNA.




Key publications: 

Arnedo-Pac, C.*, Mularoni, L., Muiños, F., Gonzalez-Perez, A., & Lopez-Bigas, N. (2019). OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers. Bioinformatics, 35(22), 4788–4790.

Arnedo-Pac, C.*, Muiños, F., Gonzalez-Perez, A., & Lopez-Bigas, N. (2022). Signatures 1 and 17 show increased propensity to create mutational hotspots in the human genome. bioRxiv 2022.09.14.507952.

Martínez-Jiménez, F., Muiños, F., Sentís, I., Deu-Pons, J., Reyes-Salazar, I., Arnedo-Pac, C.*, Mularoni, L., Pich, O., Bonet, J., Kranas, H., Gonzalez-Perez, A., & Lopez-Bigas, N. (2020). A compendium of mutational cancer driver genes. Nature reviews. Cancer, 20(10), 555–572.

Google Scholar profile

Research Associate

Contact Details

MRC Toxicology Unit
Gleeson Building
Tennis Court Road


Telephone and Email