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MRC Toxicology Unit

MRC Programme Leader – Immunology
Director of Research level, Grade 12, Competitive Salary
Closing Date: Sunday 9th June 2019
Reference: PU19023
The MRC Toxicology Unit is a leading International Research Institute within the School of Biological Sciences, University of Cambridge. The Unit delivers high impact mechanistic toxicology research, pursuing hypothesis-driven toxicological questions with a particular focus on the study of the causal links between exposure to endogenous and exogenous toxicants, molecular initiating events and adverse outcome pathways.

We are seeking to recruit a Programme Leader, at Director of Research level, to the Unit’s new Inflammatory Responses and Immune Regulation theme. We would be particularly interested in research programmes which include the study of adverse effects on the immune system resulting from therapeutic exposure to biologics, e.g. immune modulators and CAR- T cells, adverse immune responses to chemicals and environmental agents including respiratory tract allergies or autoimmunity, although other areas relevant to immuno-toxicology will be considered.

The position comes with an attractive research funding package, including core-funded postdoctoral posts and PhD studentships.

Applicants must have a PhD and an international reputation within their field.

This is an open-ended position funded by the Medical Research Council, renewable every 5 years.

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MRC Postdoctoral Fellow
Research Associate level, Grade 7 (£32,236-£39,609)
Closing Date: Wednesday 19th June 2019
Reference: PU19151
We are looking to appoint an MRC Postdoctoral Fellow (PF) to join Miguel Martins’s lab ‘Mitochondria and cell death regulation following toxic injury’. We employ multi-disciplinary approaches, including Drosophila genetics, quantitative fly behaviour analysis, RNAseq, metabolomics, quantitative proteomics, and microbiome analysis, to understand the consequences of mitochondrial dysfunction.

Applicants must hold, or be close to completing, a PhD in a relevant discipline such as Neurobiology or Immunology together with experience in Drosophila genetics and biochemical techniques; experience in expression in sleep analysis; in vivo functional imaging and neuronal tracing is desirable. Submission of at least one first author international peer-reviewed paper is expected as is the ability to work both independently and as part of a team, together with excellent communication and critical thinking skills.

This is a three year training and development position.

More details/ apply