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Current Vacancies:

- Research Assistant (Microbiology) (Fixed Term)

£26,715 - £30,942, Reference PU26554, Closing date 3 June 2021

Patil lab at MRC-Toxicology Unit is looking for a microbiology Research Assistant to contribute to its programme on Microbiome-mediated Toxicity of Xenobiotics. An adult individual typically harbours a few hundred grams of bacteria in their digestive tract. Recent findings have brought forward the fundamental role of this microbiota in determining drug efficacy, mode of action and side effects. Yet, such interactions at the microbiome level remain unknown for most of the drugs and for other xenobiotics that we are exposed to (e.g., food contaminants like pesticides). The overarching goal of our research is to discover and model complex (xeno-) metabolic networks emerging in the gut microbiota and thereby gain mechanistic insights into microbiome-mediated toxicity.

Applicants must hold, or be close to completing, a degree in a relevant discipline (e.g., microbiology, cell biology or molecular biology) and have experience in microbial cultivation. Experience in anaerobic culturing and/or genetic engineering is desired. The Patil lab is home to researchers representing a wide range of expertise, ranging from mathematical modelling to metabolomics. Enthusiasm for working in a diverse inter-disciplinary team is therefore a must.

Fixed-term: The funds for this post are available for 3 years in the first instance.

 

- Research Associate (Fixed Term)

£32,816 - £40,322, Reference PU26314, Closing date 2 June 2021

We are looking for a postdoctoral Research Associate to join an ERC-funded project in the Patil lab aimed at targeted modulation of kefir and gut microbial communities. The candidate will contribute by developing new concepts and tools for microbial community modelling. The project is highly interdisciplinary, integrating computational (ODE-based and genome-scale metabolic models) and experimental approaches (high-throughput microbiomics, RNAseq, and metabolomics), and offers exciting possibilities for rational engineering of microbial communities.

Applicants must hold, or be close to completing, a PhD in a relevant discipline (e.g. first-principle modelling, bioinformatics or statistical data analysis). The post will be ideal for a candidate with experience in modelling of complex systems such as metabolism or ecological networks. Experience in large-scale data analysis (e.g. transcriptomics or metabolomics data) is also desirable. We are particularly interested in candidates with enthusiasm for exploring new concepts and working in close collaboration with experimental researchers. The Patil lab is home to researchers representing a wide range of expertise, ranging from mathematical modelling to metabolomics. Enthusiasm for working in a diverse inter-disciplinary team is therefore a must.

Fixed-term: The funds for this post are available for 4 years in the first instance.

 

 

- CAMS Research Fellowship in Epigenetics & Toxicology (Fixed Term)

£32,816 - £40,322, Reference PU26314, Closing date 12 May 2021

The Cambridge Alliance on Medicines Safety (CAMS: https://www.ats.cam.ac.uk/what-we-do/cambridge-alliance-medicines-safety) is delighted to be able to invite applications for a Junior Research Fellowship in epigenetic drug safety and toxicology.

This prestigious post-doctoral research fellowship aims to attract one of the very best early career researchers to Cambridge to develop a career in medicines safety science. The fellowship is intended to serve as a step towards independence in academic research. Successful applicants will have obtained a PhD in a relevant discipline and typically have had some postdoctoral experience.

This position will be based at the MRC Toxicology Unit within the Gleeson Building, Tennis Court Road, Cambridge.

Of interest to those wishing to apply, CAMS is hosting a virtual half-day symposium on Monday 19th April 2021 exploring the "Safety of Epigenetic Drugs": Please register your interest here: https://www.eventbrite.co.uk/e/cams-epigenetic-safety-event-tickets-146594296487

We are seeking highly-motivated individuals with excellent communication skills who are able to work effectively as part of a multi-disciplinary team. Given the opportunities enabled under the Alliance with AstraZeneca and GlaxoSmithKline, applicants should also be able to demonstrate a specific interest in collaborating with industry to translate their research. Candidates should show exceptional initiative and demonstrate a capacity for innovation and independent thought.

Further information regarding CAMS Junior Research Fellowships can be found at: https://www.ats.cam.ac.uk/what-we-do/cambridge-alliance-medicines-safety/cambridge-alliance-medicines-safety-junior-research

Fixed-term: The funds for this post are available for 3 years in the first instance.