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MRC Toxicology Unit

 

The Advanced Light Imaging Section provides a wide range of instruments and software for the acquisition, processing and analysis of light-captured images. The equipment is used by all Unit Research Groups together with external collaborators.

Within the Toxicology Unit, we have a range of instruments to capture images from a variety of experimental situations. The systems include three-scanning confocal microscopes (LSM 510 and LSM880), two of which are equipped with Mai Tai pulsing IR lasers for multi-photon imaging. Live cells can be imaged with an on-stage incubation system.

In addition, we have a new spinning-disk confocal incorporating a steerable UV ablation laser for DNA damage and other studies.

The Unit has a number of large wide-field microscope systems which are dedicated to time-lapse, calcium and live-cell imaging.

Support and user training is provided for all the instruments as well as help in analysing results.

 

Mouse embryonic stem cell derived neuronal cells.

Courtesy of Dr Lia Panman, Toxicology Unit

CHO M1 WT cells.

Courtesy of Dr Sophie Bradley, Toxicology Unit.

Stem cell derived dopaminergic neurons.

Courtesy of Dr Anthony Oosterveen, Toxicology Unit.

Group members