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Frequently, various types of gene regulatory relations and interactions are experimentally validated based on the cell lines models.

 

The obvious next question, whether the discovered gene regulatory model is valid in various clinical conditions and/or has any influence on patient survival. To address these questions we start multiple projects which rely on analyses of available gene expression profiling data (GEO Omnibus Data Mining). Statistical methods are applied to provide robust tools to address complex and specific questions regarding gene regulation in cancer. For more details please visit GEO Omnibus Data Mining“.