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Angela completed a degree in Biotechnology followed by a Master's degree in Biomedicine at the University Pablo de Olavide (Seville, Spain). In 2017, she obtained a PhD at the Institute of Fuctional Biology and Genomics in Salamanca, Spain. During this time, she studied the coordination of growth and cell cycle in yeast. She also spent few months as a visiting student in Raul Duran's laboratory in Bordeaux (France) where she learnt different strategies to modulate mTOR activity in mammalian cells. Then, she moved to Cambridge to join Professor Juan Mata's laboratory as a postdoc and work on translation regulation under stress conditions using Ribo-seq. In 2020, Angela joined Anne Willis group at the MRC Toxicology Unit to study the post-transcriptional, molecular pathways triggered by exposure to toxic fibres that leads to mesothelioma.


Research interests:

She became interested in cancer biology and cancer models but also in proteomics techniques, identification of RNA-protein interactions and bioinformatic analyses.



Key publications: 

Rubio A, Garland GD, Sfakianos A, Harvey RF, Willis AE. Aberrant protein synthesis and cancer development: The role of canonical eukaryotic initiation, elongation and termination factors in tumorigenesis. Semin Cancer Biol. 2022 Nov;86(Pt 3):151-165. doi: 10.1016/j.semcancer.2022.04.006. Epub 2022 Apr 26. PMID: 35487398.
Rubio A, Ghosh S, Mülleder M, Ralser M, Mata J. Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast. Nucleic Acids Res. 2021 Jan 11;49(1):383-399. doi: 10.1093/nar/gkaa1180. PMID: 33313903; PMCID: PMC7797079.
Rubio A, García-Blanco N, Vázquez-Bolado A, Belén Suárez M, Moreno S. Nutritional cell cycle reprogramming reveals that inhibition of Cdk1 is required for proper MBF-dependent transcription. J Cell Sci. 2018 Sep 20;131(18):jcs218743. doi: 10.1242/jcs.218743. PMID: 30154212.

MRC Postdoctoral Fellow

Contact Details

MRC Toxicology Unit
Gleeson Building
Tennis Court Road